Among the most discussed issues of the research area of philosophy of computing these days are certainly the nature, methodology and experimental characteristics of Software Intensive Science. A recent article in Philosophy & Technology by John Symons, Jack Horner has explicitly approached SIS, available here:
http://link.springer.com/article/10.1007/s13347-014-0163-x
The article is followed by two short comment papers, by Nicola Angius here
http://link.springer.com/article/10.1007/s13347-014-0173-8
and by Giuseppe Primiero, here